Mexico City is easier when each day has one clear neighbourhood shape. Choose a cultural anchor, add a generous meal and leave enough time for the city to surprise you.
Start with a neighbourhood
Keep the first day close to your accommodation. Roma, Condesa, Centro and Coyoacán each create a different rhythm, so choose one area instead of crossing the city repeatedly.
Use museums as anchors
Pick one major museum or historic place, then make the next stop food, a park or a quiet café. This keeps the day interesting for different ages and energy levels.
Plan the practical details
Build in traffic time, use official transport guidance and keep a little flexibility for rain, queues and an unexpectedly long lunch.